SIRT1/Atg5/autophagy are involved in the antiatherosclerosis effects of ursolic acid

Abstract

The purpose of this study was to investigate the antiatherosclerosis effects of ursolic acid (UA) in high-fat diet-fed quails (Coturnix coturnix) and potential mechanism. Quails were treated with high-fat diet (14 % pork oil, 1 % cholesterol w/w) with or without UA (50, 150, or 300 mg/kg/day) for 10 weeks. Serum lipid profile was assessed at 0, 4.5, and 10… (More)
DOI: 10.1007/s11010-016-2787-x

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