SIRS-associated coagulopathy and organ dysfunction in critically ill patients with thrombocytopenia.

@article{Ogura2007SIRSassociatedCA,
  title={SIRS-associated coagulopathy and organ dysfunction in critically ill patients with thrombocytopenia.},
  author={Hiroshi Ogura and Satoshi Gando and Toshiaki Iba and Yutaka Eguchi and Yasuhiro Ohtomo and Kohji Okamoto and Kazuhide Koseki and Toshihiko Mayumi and Atsuo Murata and Toshiaki Ikeda and Hiroyasu Ishikura and Masashi Ueyama and Shigeki Kushimoto and D. Saitoh and Shigeatsu Endo and Shuji Shimazaki},
  journal={Shock},
  year={2007},
  volume={28 4},
  pages={
          411-7
        }
}
BACKGROUND Coagulopathy and thrombocytopenia often occur in critically ill patients, and disseminated intravascular coagulation (DIC) can lead to multiple organ dysfunction and a poor outcome. However, the relation between coagulopathy and systemic inflammatory response has not been thoroughly clarified. Thus, we evaluated coagulative activity, organ dysfunction, and systemic inflammatory response syndrome (SIRS) in critically ill patients with thrombocytopenia and examined the balance between… CONTINUE READING
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