SIRPα interacts with nephrin at the podocyte slit diaphragm.

@article{Kajiho2012SIRPIW,
  title={SIRPα interacts with nephrin at the podocyte slit diaphragm.},
  author={Yuko Kajiho and Yutaka Harita and Hidetake Kurihara and Shigeru Horita and Atsuko Matsunaga and Haruko Tsurumi and Shoichiro Kanda and Noriko Sugawara and Kenichiro Miura and Takashi Sekine and Seisuke Hattori and Motoshi Hattori and Takashi Igarashi},
  journal={The FEBS journal},
  year={2012},
  volume={279 17},
  pages={3010-21}
}
The slit diaphragm (SD) is an intercellular junction between renal glomerular epithelial cells (podocytes) that is essential for permselectivity in glomerular ultrafiltration. The SD components, nephrin and Neph1, assemble a signaling complex in a tyrosine phosphorylation dependent manner, and regulate the unique actin cytoskeleton of podocytes. Mutations… CONTINUE READING