SIOPEL trials using preoperative chemotherapy in hepatoblastoma.

  title={SIOPEL trials using preoperative chemotherapy in hepatoblastoma.},
  author={Giorgio Perilongo and Elisabeth Shafford and Jack Plaschkes},
  journal={The Lancet. Oncology},
Hepatoblastoma is a rare, malignant liver tumour of childhood. Until the mid 1980s only around 30% of patients were cured, but with modern chemotherapy, and of course surgery, the cure rate is now at least 70%. This dramatic improvement in survival has been achieved by the national and international cooperation of paediatric oncology centres. The International Society of Paediatric Oncology Liver Tumour Group, in contrast to most other groups, has used preoperative chemotherapy in all patients… CONTINUE READING