SINE extinction preceded LINE extinction in sigmodontine rodents: implications for retrotranspositional dynamics and mechanisms

@article{Rinehart2005SINEEP,
  title={SINE extinction preceded LINE extinction in sigmodontine rodents: implications for retrotranspositional dynamics and mechanisms},
  author={T. Rinehart and R. Grahn and H. Wichman},
  journal={Cytogenetic and Genome Research},
  year={2005},
  volume={110},
  pages={416 - 425}
}
  • T. Rinehart, R. Grahn, H. Wichman
  • Published 2005
  • Biology, Medicine
  • Cytogenetic and Genome Research
  • Short Interspersed Nuclear Elements, or SINEs, retrotranspose despite lacking protein-coding capability. It has been proposed that SINEs utilize enzymes produced in trans by Long Interspersed Nuclear Elements, or LINEs. Strong support for this hypothesis is found in LINE and SINE pairs that share sequence homology; however, LINEs and SINEs in primates and rodents are only linked by an insertion site motif. We have now profiled L1 LINE and B1 SINE activity in 24 rodent species including… CONTINUE READING
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