SIN-1 has no direct myocardial anti-ischemic action.

  title={SIN-1 has no direct myocardial anti-ischemic action.},
  author={Gisbert Kober and Meredith Bender and Christian Vallbracht and Horst Sievert and Harald Klepzig},
  journal={Clinical cardiology},
  volume={16 10},
Anti-ischemic drugs may develop their cardiac activity via peripheral (reduction in preload and/or afterload) or cardiac (coronary vasculature, myocardial cell metabolism) effects. The aim of the study was to investigate whether SIN-1, the active metabolite of molsidomine, develops a direct myocardial anti-ischemic property. Three groups of seven patients… CONTINUE READING