SILAC-Based Quantitative Strategies for Accurate Histone Posttranslational Modification Profiling Across Multiple Biological Samples.

Abstract

Histone posttranslational modifications (hPTMs) play a key role in regulating chromatin dynamics and fine-tuning DNA-based processes. Mass spectrometry (MS) has emerged as a versatile technology for the analysis of histones, contributing to the dissection of hPTMs, with special strength in the identification of novel marks and in the assessment of… (More)

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Cite this paper

@article{Cuomo2017SILACBasedQS, title={SILAC-Based Quantitative Strategies for Accurate Histone Posttranslational Modification Profiling Across Multiple Biological Samples.}, author={Alessandro Cuomo and Monica Soldi and Tiziana Bonaldi}, journal={Methods in molecular biology}, year={2017}, volume={1528}, pages={97-119} }