SIFamide acts on fruitless neurons to modulate sexual behavior in Drosophila melanogaster

@article{Sellami2015SIFamideAO,
  title={SIFamide acts on fruitless neurons to modulate sexual behavior in Drosophila melanogaster},
  author={Azza Sellami and Jan A Veenstra},
  journal={Peptides},
  year={2015},
  volume={74},
  pages={50-56}
}
The Drosophila gene fruitless expresses male and female specific transcription factors which are responsible for the generation of male specific neuronal circuitry for courtship behavior. Mutations in this gene may lead to bisexual behavior in males. Bisexual behavior in males also occurs in the absence of the neuropeptide SIFamide. We show here that the SIFamide neurons do not express fruitless. However, when fruitless neurons are made to express RNAi specific for the SIFamide receptor, male… CONTINUE READING
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