SIFT2: Enabling dense quantitative assessment of brain white matter connectivity using streamlines tractography

@article{Smith2015SIFT2ED,
  title={SIFT2: Enabling dense quantitative assessment of brain white matter connectivity using streamlines tractography},
  author={Robert E. Smith and Jacques-Donald Tournier and Fernando Calamante and Alan Connelly},
  journal={NeuroImage},
  year={2015},
  volume={119},
  pages={338-351}
}
Diffusion MRI streamlines tractography allows for the investigation of the brain white matter pathways non-invasively. However a fundamental limitation of this technology is its non-quantitative nature, i.e. the density of reconstructed connections is not reflective of the density of underlying white matter fibres. As a solution to this problem, we have previously published the "spherical-deconvolution informed filtering of tractograms (SIFT)" method, which determines a subset of the… CONTINUE READING
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