SIAMESE cooperates with the CDH1-like protein CCS52A1 to establish endoreplication in Arabidopsis thaliana trichomes.

@article{Kasili2010SIAMESECW,
  title={SIAMESE cooperates with the CDH1-like protein CCS52A1 to establish endoreplication in Arabidopsis thaliana trichomes.},
  author={Remmy Kasili and Jason D. Walker and Lyle A Simmons and Jing Zhou and Lieven De Veylder and John C Larkin},
  journal={Genetics},
  year={2010},
  volume={185 1},
  pages={257-68}
}
Endoreplication, also known as endoreduplication, is a phyogenetically widespread modified version of the cell cycle in which DNA replication is not followed by cell division. The SIAMESE (SIM) gene of Arabidopsis thaliana encodes the founding member of a novel class of plant-specific cyclin-dependent kinase (CDK) inhibitors and is a key regulator of endoreplication during the development of trichomes (shoot epidermal hairs). Here, we have identified mutations in the CCS52A1 gene as genetic… CONTINUE READING