SHV-7, a novel cefotaxime-hydrolyzing beta-lactamase, identified in Escherichia coli isolates from hospitalized nursing home patients.

@article{Bradford1995SHV7AN,
  title={SHV-7, a novel cefotaxime-hydrolyzing beta-lactamase, identified in Escherichia coli isolates from hospitalized nursing home patients.},
  author={Patricia A Bradford and Carl Urban and Arun Jaiswal and Noriel Mariano and Beth A. Rasmussen and Steven J. Projan and James J. Rahal and Karen Bush},
  journal={Antimicrobial agents and chemotherapy},
  year={1995},
  volume={39 4},
  pages={899-905}
}
Four ceftazidime-resistant Escherichia coli strains were isolated from elderly nursing home patients in a New York hospital during 1993. Strains MCQ-2, MCQ-3, and MCQ-4 were determined to be identical by pulsed-field gel electrophoresis and plasmid profiles, whereas strain MCQ-1 was unique. Strain MCQ-1 was determined to produce a TEM-10 beta-lactamase. Strains MCQ-2, MCQ-3, and MCQ-4 were also noted to be resistant to cefotaxime. These three strains produced two beta-lactamases with pIs of 5.4… CONTINUE READING

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