SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing.

@article{Dohm2007SHARCGSAF,
  title={SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing.},
  author={Juliane C. Dohm and Claudio Lottaz and T. S. Borodina and Heinz Himmelbauer},
  journal={Genome research},
  year={2007},
  volume={17 11},
  pages={1697-706}
}
The latest revolution in the DNA sequencing field has been brought about by the development of automated sequencers that are capable of generating giga base pair data sets quickly and at low cost. Applications of such technologies seem to be limited to resequencing and transcript discovery, due to the shortness of the generated reads. In order to extend the fields of application to de novo sequencing, we developed the SHARCGS algorithm to assemble short-read (25-40-mer) data with high accuracy… CONTINUE READING
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