SGE‐102: A novel therapy for refractory status epilepticus

@article{Reddy2013SGE102AN,
  title={SGE‐102: A novel therapy for refractory status epilepticus},
  author={Kiran Reddy and R A Reife and Andrew J. Cole},
  journal={Epilepsia},
  year={2013},
  volume={54}
}
Refractory status epilepticus (SE) has a mortality rate of up to 35%. Current treatment protocols for the treatment of SE begin with benzodiazepines and then proceed to conventional anticonvulsants. If seizures continue, SE is considered refractory (RSE) and treatment with anesthetic agents in undertaken. Twenty‐four h to 48 h after initiation of anesthesia with midazolam, pentobarbital or thiopental, or propofol, an attempt is made to wean the anesthetic. If this fails and seizures recur, SE… 
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