SET for life: biochemical activities and biological functions of SET domain-containing proteins.

@article{Herz2013SETFL,
  title={SET for life: biochemical activities and biological functions of SET domain-containing proteins.},
  author={H. Herz and Alexander S. Garruss and Ali Shilatifard},
  journal={Trends in biochemical sciences},
  year={2013},
  volume={38 12},
  pages={621-39}
}
SET domain-containing proteins belong to a group of enzymes named after a common domain that utilizes the cofactor S-adenosyl-L-methionine (SAM) to achieve methylation of its substrates. Many SET domain-containing proteins have been shown to display catalytic activity towards particular lysine residues on histones, but emerging evidence also indicates that various nonhistone proteins are specifically targeted by this clade of enzymes. Here, we summarize the most recent findings on the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 326 references

Control of the hippo pathway by set7dependent methylation of yap

  • 284 Oudhoff, M.J
  • Dev. Cell
  • 2013

Similar Papers

Loading similar papers…