Corpus ID: 212577486

SERUM VISFATIN AND LIPID PROFILES IN PATIENTS WITH TYPE II DIABETES IN COMPARISON WITH HEALTHY CONTROLS IN KHARTOUM STATE-SUDAN

@inproceedings{Hamza2015SERUMVA,
  title={SERUM VISFATIN AND LIPID PROFILES IN PATIENTS WITH TYPE II DIABETES IN COMPARISON WITH HEALTHY CONTROLS IN KHARTOUM STATE-SUDAN},
  author={B. M. Hamza and Fatima M. Osman and Afrah and Gasmallh Babeker and A Saeed and Tasabeeh Elser and Nassr Eldin Mohammed Ahmed Shrif},
  year={2015}
}
Visfatin is an adipocytokine which is secreted largely by visceral adipose tissue. It acts synergistically with insulin in increasing glucose cellular uptake, it also has an insulin-like effects through direct connection and activation of insulin receptors without any change or competition with the insulin .The aim of this study was to explore the relation of serum visfatin and lipid profile in T2DM in the context of the role of glycemic control. A total of 45 T2DM Sudanese patients and 45… Expand

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References

SHOWING 1-10 OF 13 REFERENCES
Lipid Profiles and Serum Visfatin Concentrations in Patients with Type II Diabetes in Comparison with Healthy Controls
TLDR
An inverse relationship between circulating level of visfatin and fasting blood glucose is documented, which may suggest the role of increased visFatin level and increase in synthesis and secretion of the cytokines from adipocytes in diabetic and pre-diabetic individuals. Expand
Visfatin levels are low in subjects with type 2 diabetes compared to age-matched controls
TLDR
The data suggest that visfatin may be a marker of subclinical inflammatory state in patients with type 2 diabetes compared to the age-matched control subjects without DM, and correlated strongly with resistin and CRP. Expand
Serum visfatin increases with progressive beta-cell deterioration.
Visfatin has shown to be increased in type 2 diabetes but to be unrelated to insulin sensitivity. We hypothesized that visfatin is associated with insulin secretion in humans. To this aim, aExpand
Vaspin and visfatin/Nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus.
TLDR
Both vaspin and visfatin/Nampt might play an important role in the pathogenesis of T2DM and their levels were found to be significantly positively correlated with each other and with other biochemical parameters. Expand
Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus.
TLDR
Results indicate that visfatin may play a role in the pathogenesis of type 2 diabetes mellitus and multiple logistic regression analysis revealed visFatin as an independent association factor for T2DM, even after full adjustment of known biomarkers. Expand
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TLDR
Since evidence of a direct link between visfatin genotype and human type 2 diabetes mellitus is still weak, more molecular, physiological and clinical studies are needed to determine the role of visFatin in the etiology and pathogenesis of type 2abetes mellitus. Expand
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.
TLDR
SAT VF is highly expressed in lean, more insulin-sensitive subjects and is attenuated in subjects with high IMCL, low S(I), and high levels of inflammatory markers, and VAT VF and SAT VF are regulated oppositely with BMI. Expand
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.
TLDR
Visceral and subcutaneous adipose tissue display important metabolic differences that underlie the association of visceral obesity with obesity-related cardiovascular and metabolic alterations, but correlation with measures of obesity but not with visceral fat mass or waist-to-hip ratio is found. Expand
CORRELATIONS OF VISFATIN WITH THE LIPIDIC METABOLISM IN DIABETIC AND OBESE PATIENTS
TLDR
Visfatin is an adipocytokine identified in 2005, its name suggests that it is predominantly produced in visceral fat, which is identical to the PBEF, that was described in 1994 as a lymphocytes produced cytokine. Expand
Visfatin/PBEF and atherosclerosis-related diseases.
TLDR
There is evidence that visfatin expression and circulating levels are influenced by fat area and distribution, inflammatory state, renal function, iron metabolism, hormones as well as several other factors, and more research is needed to better understand the factors that control its synthesis/release. Expand
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