SERUM STEROIDS AND PITUITARY HORMONES IN FEMALE PUBERTY: A PARTLY LONGITUDINAL STUDY

@article{Apter1980SERUMSA,
  title={SERUM STEROIDS AND PITUITARY HORMONES IN FEMALE PUBERTY: A PARTLY LONGITUDINAL STUDY},
  author={Dan L Apter},
  journal={Clinical Endocrinology},
  year={1980},
  volume={12}
}
  • D. Apter
  • Published 1 February 1980
  • Medicine, Biology
  • Clinical Endocrinology
Pubertal development of 200 normal girls, 7–17 years of age, was investigated in a partly longitudinal manner with two examinations 1·5 years apart. Samples from postmenarchal girls were taken on days 6–9 and 20–23 of the menstrual cycle. Serum pregnenolone, progesterone, 17‐hydroxyprogesterone, dehydroepiandrosterone, androstenedione, testosterone, 5α‐dihydrotestosterone, androsterone, oestradiol and cortisol as well as ACTH, FSH, LH and prolactin were measured radioimmunologically and were… 
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  • Medicine
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TLDR
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References

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TLDR
Levels of LH and Prog levels indirectly suggest that ovulation occurs in a few girls within months after menarche, more than expected during the luteal phase.
Serum pregnenolone, progesterone, 17-hydroxyprogesterone, testosterone and 5 alpha-dihydrotestosterone during female puberty.
  • D. Apter, R. Vihko
  • Medicine, Biology
    The Journal of clinical endocrinology and metabolism
  • 1977
TLDR
Serum pregnenolone, progesterone, 17-hydroxyprogesterone, testosterone and 5α-dihydrotestosterone concentrations were measured radio-immunologically from a group of 200 normal girls 7–17 years of age to study the effects of bone age, breast and pubic hair developmental stages, and gynecological age on steroids.
ADRENAL AND GONADAL STEROIDS IN GIRLS DURING SEXUAL MATURATION
TLDR
Both gonadotrophin values were significantly lower in these P4–5 pre‐menarchal girls than those found in adult women in the early follicular phase, and no significant changes were found in plasma Prl, cortisol and 17P levels during pubertal development; in contrast, plasma concentrations of DHA tripled from P1 to P 4–5, reaching adult levels.
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TLDR
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TLDR
Plasma estrogens correlated better with the clinical evaluation of sexual maturation than with chronological ages in the girls, and the boys showed better relationship between the androgens and maturational stages than with Chronological age.
ADRENOCORTICAL FUNCTION IN PUBERTY Serum ACTH, Cortisol and Dehydroepiandrosterone in Girls and Boys
TLDR
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TLDR
It is suggested that the initial hormonal event of female puberty is increased gonadotropin secretion, especially FSH, which rises sharply at the onset of puberty, but plate...
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TLDR
Early rise in the course of pubertal development of the two sex steroids predominantly of adrenal origin, DHA and delta, and its occurence 1 to 2 years earlier in girls than in boys, as does puberty itself, suggest a possible role for these steroids in the mechanisms involved in triggering the hypothalamic-pituitary-gonadal axis at puberty.
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TLDR
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TLDR
In girls, there was a correlation between serum LH and body weight, as well as calculated fat amount and body fat percentage early in puberty, which suggests that the correlation found is not due to age‐related parallel phenomena.
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