SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder.

Abstract

BACKGROUND SERT I425V, an uncommon missense single nucleotide polymorphism producing a gain-of-function of the serotonin transporter (SERT), was originally found to segregate with a primarily obsessive-compulsive disorder (OCD) but complexly comorbid phenotype in two unrelated families. OBJECTIVE As two individuals with SERT I425V and OCD also had… (More)
DOI: 10.1097/YPG.0b013e3282f08a06

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