SERPINB5 and AKAP12 -- Expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma

@inproceedings{Mardin2010SERPINB5AA,
  title={SERPINB5 and AKAP12 -- Expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma},
  author={Wolf Arif Mardin and Kostadin O Petrov and Andreas Enns and N. Senninger and J{\"o}rg Haier and Soeren Torge Mees},
  booktitle={BMC Cancer},
  year={2010}
}
Early metastasis and infiltration are survival limiting characteristics of pancreatic ductal adenocarcinoma (PDAC). Thus, PDAC is likely to harbor alterations in metastasis suppressor genes that may provide novel diagnostic and therapeutic opportunities. This study investigates a panel of metastasis suppressor genes in correlation to PDAC phenotype and examines promoter methylation for regulatory influence on metastasis suppressor gene expression and for its potential as a diagnostic tool… CONTINUE READING