SEROTONIN‐LSD INTERACTIONS

@article{Gaddum1957SEROTONINLSDI,
  title={SEROTONIN‐LSD INTERACTIONS},
  author={J. H. Gaddum},
  journal={Annals of the New York Academy of Sciences},
  year={1957},
  volume={66}
}
  • J. H. Gaddum
  • Published 1 March 1957
  • Chemistry, Medicine
  • Annals of the New York Academy of Sciences
About 5 years ago various workers in my laboratory started to look for drugs that would antagonize the actions of 5-hydroxytryptamine (5-HT, enteramine, serotonin). Many indole compounds depressed the responses of plain muscles, but this effect was generally unspecific, since the effects of other stimulant drugs were also depressed. The action of 5-HT on the rat’s uterus was depressed by gamine, however, and this effect was specific because the action of acetylcholine was not depressed, so that… 

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TLDR
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