SERMs: progress and future perspectives.

  title={SERMs: progress and future perspectives.},
  author={James H. Pickar and Tanya MacNeil and Kathleen M Ohleth},
  volume={67 2},
Selective estrogen receptor modulators (SERMs) interact with estrogen receptors as agonists or antagonists depending on the target tissue. Currently available SERMs are used to treat and prevent breast cancer and osteoporosis, to treat ovulatory dysfunction in women, and for contraception. Because current therapies do not adequately treat menopausal symptoms, the search continues for the optimal SERM for postmenopausal women, which would relieve hot flushes, treat vaginal atrophy, and prevent… CONTINUE READING


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