SERCA pump isoform expression in endothelium of veins and arteries: Every endothelium is not the same

@article{Khan2000SERCAPI,
  title={SERCA pump isoform expression in endothelium of veins and arteries: Every endothelium is not the same},
  author={Islam Zeb Khan and Vicky Sandhu and Christine Misquitta and A. K. Grover},
  journal={Molecular and Cellular Biochemistry},
  year={2000},
  volume={203},
  pages={11-15}
}
Endothelium from rat aorta expresses sarco/endoplasmic reticulum Ca2+(SERCA) pump gene SERCA3 where as the smooth muscle expresses SERCA2. This has led to the postulate that vascular endothelium expresses SERCA3. To test this postulate, we examined the SERCA2 and SERCA3 mRNA expression in endothelium and smooth muscle dissected from coronary artery, coronary vein, aorta and vena cava of pig. Smooth muscle from all arteries and veins expressed only the SERCA2 mRNA. Endothelium from coronary… CONTINUE READING

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