SEM/EDX and confocal Raman microscopy as complementary tools for the characterization of pharmaceutical tablets.

@article{Scoutaris2014SEMEDXAC,
  title={SEM/EDX and confocal Raman microscopy as complementary tools for the characterization of pharmaceutical tablets.},
  author={Nikolaos Scoutaris and Kapilkumar Vithani and Ian J. Slipper and Babur Z. Chowdhry and Dennis Douroumis},
  journal={International journal of pharmaceutics},
  year={2014},
  volume={470 1-2},
  pages={88-98}
}
The drug distribution on the surface of hot-melt extruded, pre-mixed hot-melt extruded and direct compressed tablet formulations was characterized by using scanning electron microscopy, energy dispersive X-ray spectroscopy (EDX) and confocal Raman spectroscopy. Formulations of paracetamol (PMOL) and Compritol(®) (C-888) were extruded using hot-melt… CONTINUE READING