SEGRAs: a novel class of anti-inflammatory compounds.

@article{Schcke2002SEGRAsAN,
  title={SEGRAs: a novel class of anti-inflammatory compounds.},
  author={Heike Sch{\"a}cke and Hartwig H Hennekes and A Schottelius and Stefan Jaroch and Mark Lehmann and Norbert Schmees and Hartmut Rehwinkel and Khusru Asadullah},
  journal={Ernst Schering Research Foundation workshop},
  year={2002},
  volume={40},
  pages={357-71}
}
Dissociated GCs show a separation between anti-inflammatory effects and certain side effects. This renders them as attractive compounds with better effect/side-effect profile as promising drug candidates and tool compounds for analyzing the molecular mechanisms of single side effects. A number of the GC-mediated side effects (e.g., osteoporosis, skin atrophy) are regulated in a very complex manner and use more than one molecular mechanism of the GR. Thus, theoretical predictions about the… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…