SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development

@inproceedings{Vera2013SCOspondinFE,
  title={SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development},
  author={Am{\'e}rica Vera and Karen Stanic and Hernan A Montecinos and Marcela E. Torrej{\'o}n and Sonia Marcellini and Teresa Caprile},
  booktitle={Front. Cell. Neurosci.},
  year={2013}
}
The central nervous system (CNS) develops from the neural tube, a hollow structure filled with embryonic cerebrospinal fluid (eCSF) and surrounded by neuroepithelial cells. Several lines of evidence suggest that the eCSF contains diffusible factors regulating the survival, proliferation, and differentiation of the neuroepithelium, although these factors are only beginning to be uncovered. One possible candidate as eCSF morphogenetic molecule is SCO-spondin, a large glycoprotein whose secretion… CONTINUE READING
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  • Vera, Stanic, Montecinos, Torrejón, Marcellini, Caprile
  • 2013

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