SCN lesions block responses to systemic melatonin infusions in Siberian hamsters.

@article{Bartness1991SCNLB,
  title={SCN lesions block responses to systemic melatonin infusions in Siberian hamsters.},
  author={Timothy J Bartness and Bruce D. Goldman and Eric L Bittman},
  journal={The American journal of physiology},
  year={1991},
  volume={260 1 Pt 2},
  pages={
          R102-12
        }
}
The role of the suprachiasmatic nuclei (SCN) in the response to short-day melatonin (MEL) signals was examined in long-day-housed pinealectomized (PINX) Siberian hamsters. Five- or ten-hour MEL infusions that mimicked the peak nocturnal durations of serum MEL levels in long or short days, respectively, or control saline infusions were given for 5 wk. Half the hamsters in each infusion group also received bilateral electrolytic SCN lesions. The 10-h MEL infusions reduced testes weight, body and… CONTINUE READING

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