SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.

@article{Sangoi2017SATB2EI,
  title={SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.},
  author={Ankur R. Sangoi and Malti Kshirsagar and Andrew E Horvai and Andres Anibal Roma},
  journal={International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists},
  year={2017},
  volume={36 2},
  pages={140-145}
}
The novel marker special AT-rich sequence binding protein (SATB2) is highly sensitive for mesenchymal tumors with osteoblastic differentiation. However, SATB2 expression in gynecologic tract carcinosarcoma has not been previously explored. Given the potential prognostic and therapeutic implications of heterologous carcinosarcoma in the gynecologic tract, this study investigates the utility of SATB2 in identifying osteosarcomatous elements. A multi-institution database review identified… CONTINUE READING