SARS-CoV-2 rapid antigen tests provide benefits for epidemic control – observations from Austrian schools

@article{Polechova2021SARSCoV2RA,
  title={SARS-CoV-2 rapid antigen tests provide benefits for epidemic control – observations from Austrian schools},
  author={Jitka Polechov'a and Kory D. Johnson and Pavel Payne and Alex Crozier and Mathias Beiglb{\"o}ck and Pavel Plevka and Eva S. Schernhammer},
  journal={Journal of Clinical Epidemiology},
  year={2021},
  volume={145},
  pages={14 - 19}
}
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References

SHOWING 1-10 OF 49 REFERENCES

Longitudinal assessment of diagnostic test performance over the course of acute SARS-CoV-2 infection

RTqPCR tests will be more effective than rapid antigen tests at identifying infected individuals prior to or early during the infectious period and thus for minimizing forward transmission (provided results reporting is timely).

COVID-19 testing: One size does not fit all

By supporting the innovation, approval, manufacturing, and distribution of simpler and cheaper screening and surveillance tools, it will be possible to more effectively limit the spread of COVID-19 and respond to future pandemics.

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening

It is demonstrated that effective screening depends largely on frequency of testing and speed of reporting and is only marginally improved by high test sensitivity, and should prioritize accessibility, frequency, and sample-to-answer time.

An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam

Virological characteristics of SARS-CoV-2 vaccine breakthrough infections in health care workers

It is concluded that rare SARS-CoV-2 vaccine breakthrough infections occur, but infectious virus shedding is reduced in these cases.

The impact of SARS-CoV-2 vaccination on Alpha and Delta variant transmission

Transmission reductions declined over time since second vaccination, for Delta reaching similar levels to unvaccinated individuals by 12 weeks for ChAdOx1 and attenuating substantially for BNT162b2.

Asymptomatic COVID-19 Adult Outpatients identified as Significant Viable SARS-CoV-2 Shedders

The findings indicate that COVID-19 asymptomatic adult outpatients are significant viable SARS-CoV-2 shedders in their upper respiratory tract playing a major potential role as Sars-Cov-2 transmitters in various epidemiological transmission chains, promoting CO VID-19 resurgence in populations.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectivity by Viral Load, S Gene Variants and Demographic Factors, and the Utility of Lateral Flow Devices to Prevent Transmission

SARS-CoV-2 infectivity varies by case viral load, contact event type, and age, and the best performing LFDs detect most infectious cases are found.

Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study

COVID-19: Rapid Antigen detection for SARS-CoV-2 by lateral flow assay: a national systematic evaluation for mass-testing

The Innova LFD shows good viral antigen detection/sensitivity with excellent specificity, although kit failure rates and the impact of training are potential issues, and results support the expanded evaluation of LFDs, and assessment of greater access to testing on COVID-19 transmission.