SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases.

@article{Mertens1996SAPKA,
  title={SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases.},
  author={Stefan Mertens and Molly Craxton and Michel Goedert},
  journal={FEBS letters},
  year={1996},
  volume={383 3},
  pages={273-6}
}
Stress-activated protein kinases are MAP kinase homologues that are activated by cellular stresses, bacterial endotoxin and inflammatory cytokines. They are activated by a dual threonine/tyrosine phosphorylation within a TPY sequence in the case of stress-activated protein kinase-1 and its isoforms (also called JNKs) or a TGY sequence in the case of stress-activated protein kinase-2 and its isoforms (also called p38, p40, RK, CSBPs, XMpk2 and Mxi2). Here we report the cloning and sequencing of… CONTINUE READING
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