SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell-mediated HIV transmission.

@article{Chang2007SAMMAAM,
  title={SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell-mediated HIV transmission.},
  author={T. L. Chang and Natalia Teleshova and Aprille Rapista and Maciej T. Paluch and Robert Alan Anderson and Donald Paul Waller and Lourens J. D. Zaneveld and Angela Granelli-Piperno and Mary E. Klotman},
  journal={FEBS letters},
  year={2007},
  volume={581 24},
  pages={
          4596-602
        }
}
SAMMA, a mandelic acid condensation polymer, exhibits a broad antimicrobial activity against several sexually transmitted pathogens including human immunodeficiency virus (HIV). Here we demonstrated that SAMMA suppressed HIV transmission by dendritic cells (DCs), one of the first target cells for primary infection. The greatest inhibitory effect was achieved when SAMMA was present during the co-culture with target cells. The inhibitory effect of SAMMA on DC-mediated HIV transmission was not due… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Similar Papers

Loading similar papers…