SAGE identification of differentiation responsive genes in P19 embryonic cells induced to form cardiomyocytes in vitro

@article{Anisimov2002SAGEIO,
  title={SAGE identification of differentiation responsive genes in P19 embryonic cells induced to form cardiomyocytes in vitro},
  author={Sergey V. Anisimov and Kirill V Tarasov and Daniel R. Riordon and Anna M. Dr. Wobus and Kenneth R. Boheler},
  journal={Mechanisms of Development},
  year={2002},
  volume={117},
  pages={25-74}
}
Transcriptome profiling facilitates the identification of developmentally regulated genes. To quantify the functionally active genome of P19 embryonic carcinoma (EC) cells induced to form cardiomyocytes, we employed serial analysis of gene expression (SAGE) to sequence and compare a total of 171,735 SAGE tags from three libraries (undifferentiated P19 EC cells, differentiation days 3 + 0.5 and 3 + 3.0). After in vitro differentiation, only 3.1% of the gene products demonstrated significant (P… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Twist protein in mouse embryogenesis.

  • Developmental biology
  • 1997
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Cell culture methods and induction of differentiation of embryonal carcinoma cell lines

A. M. Rudnicki, M. W. McBurney
  • 1987
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL