S63845, an MCL-1 Selective BH3 Mimetic: Another Arrow in Our Quiver.

@article{Letai2016S63845AM,
  title={S63845, an MCL-1 Selective BH3 Mimetic: Another Arrow in Our Quiver.},
  author={Anthony Letai},
  journal={Cancer cell},
  year={2016},
  volume={30 6},
  pages={834-835}
}
A recent study reports a novel small molecule inhibitor of MCL-1 with efficacy in killing MCL-1-dependent cancer cells in vitro and in vivo. With the advent of S63845, the targeting of BCL-2, BCL-XL, and MCL-1 is now possible in vivo, but optimal clinical use is yet to be determined. 

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