S100B ranks as a new marker of multiple traumas in patients and may accelerate its development by regulating endothelial cell dysfunction.

@article{Dang2014S100BRA,
  title={S100B ranks as a new marker of multiple traumas in patients and may accelerate its development by regulating endothelial cell dysfunction.},
  author={Xingbo Dang and Laishun Guan and Wei Hu and Gongliang Du and Jun Li},
  journal={International journal of clinical and experimental pathology},
  year={2014},
  volume={7 7},
  pages={3818-26}
}
S100 calcium binding protein B (S100B) is recently known as the markers for inflammatory diseases. However, its roles and underlying mechanism on multiple-traumas remain unclearly. In this study, total 123 patients (87 male and 36 female) were enrolled and divided into two group: Injury severity score (ISS) ≥ 16 (n = 69); ISS < 16 (n = 54). ELISA assay confirmed that the circulating S100B levels in multi-trauma were obviously higher than that in healthy volunteers. Additionally, S100B… CONTINUE READING
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