S100A2 Induces Metastasis in Non–Small Cell Lung Cancer

  title={S100A2 Induces Metastasis in Non–Small Cell Lung Cancer},
  author={Etmar Bulk and B. Sargin and U. Krug and A. Hascher and Yu Jun and M. Knop and C. Kerkhoff and V. Gerke and R. Liersch and R. Mesters and M. Hotfilder and A. Marra and S. Koschmieder and M. Dugas and W. Berdel and H. Serve and C. M{\"u}ller-Tidow},
  journal={Clinical Cancer Research},
  pages={22 - 29}
  • Etmar Bulk, B. Sargin, +14 authors C. Müller-Tidow
  • Published 2009
  • Biology, Medicine
  • Clinical Cancer Research
  • Purpose: S100 proteins are implicated in metastasis development in several cancers. In this study, we analyzed the prognostic role of mRNA levels of all S100 proteins in early stage non–small cell lung cancer (NSCLC) patients as well as the pathogenetic of S100A2 in the development of metastasis in NSCLC. Experimental Design: Microarray data from a large NSCLC patient cohort was analyzed for the prognostic role of S100 proteins for survival in surgically resected NSCLC. Metastatic potential of… CONTINUE READING
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