S100A13 is involved in the regulation of fibroblast growth factor-1 and p40 synaptotagmin-1 release in vitro.

@article{Carreira1998S100A13II,
  title={S100A13 is involved in the regulation of fibroblast growth factor-1 and p40 synaptotagmin-1 release in vitro.},
  author={C Mouta Carreira and Theresa M Lavallee and Francesca Tarantini and Ang{\'e}la Jackson and J T Lathrop and Brian Hampton and Wilson H. Burgess and Thomas Maciag},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 35},
  pages={22224-31}
}
We have previously characterized the release of the signal peptide sequence-less fibroblast growth factor (FGF) prototype, FGF-1, in vitro as a stress-induced pathway in which FGF-1 is released as a latent homodimer with the p40 extravesicular domain of p65 synaptotagmin (Syn)-1. To determine the biologic relevance of the FGF-1 release pathway in vivo, we sought to resolve and characterize from ovine brain a purified fraction that contained both FGF-1 and p40 Syn-1 and report that the brain… CONTINUE READING

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