S. mutans biofilm model to evaluate antimicrobial substances and enamel demineralization.

@article{CcahuanaVsquez2010SMB,
  title={S. mutans biofilm model to evaluate antimicrobial substances and enamel demineralization.},
  author={Renzo Alberto Ccahuana-V{\'a}squez and Jaime Aparecido Cury},
  journal={Brazilian oral research},
  year={2010},
  volume={24 2},
  pages={135-41}
}
The aim of this study was to validate a model of S. mutans biofilm formation, which simulated 'feast-famine' episodes of exposure to sucrose that occur in the oral cavity, showed dose-response susceptibility to antimicrobials and allowed the evaluation of substances with anticaries potential. S. mutans UA159 biofilms were grown for 5 days on bovine enamel slabs at 37 degrees C, 10% CO2. To validate the model, the biofilms were treated 2x/day with chlorhexidine digluconate (CHX) at 0.012, 0.024… CONTINUE READING

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