S. Afr. J. chem.

  title={S. Afr. J. chem.},
  author={Gerhard G. Habermehl},
Aquatricarbonyl(3,5,7-tribromotropolonato)rhenium(I) methanol solvate
The title complex, [Re(C7H2Br3O2)(CO)3(H2O)]·CH3OH, crystallized as a neutral ReI compound and one methanol solvent molecule in the asymmetric unit, complete the distorted octahedral coordination around the central metal. Expand
Cytotoxic activity of expanded coordination bis-thiosemicarbazones and copper complexes thereof
The mechanism of cytotoxicity of bis-thiosemicarbazones was proposed to be dependent on the combined effect of metal mobilisation and ROS generation which is so called a “double-punch effect” and improved significantly with Cu(II) supplementation, particularly against MCF-7 cells. Expand
Natural Products Diversity of Marine Ascidians (Tunicates; Ascidiacea) and Successful Drugs in Clinical Development
This present study reviewed the chemical diversity of marine ascidians and their pharmacological applications, challenges and recent developments in marine drug discovery reported during 1994–2014,Expand
Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases
The researchers concluded on the need for the development of MBDs to combat drug resistant parasites without causing injury to normal cells, of significance in addressing the concern World Health Organisation of ameliorating the increasing mortality rate in developing countries. Expand
Crystal structure of (E)-4-methoxy-2-{[(5-methylpyridin-2-yl)imino]methyl}phenol
The molecule of the title Schiff base compound, C14H14N2O2, displays an E conformation with respect the imine C=N double bond, with an intramolecular hydrogen bond involving the phenolic H and imine N atoms. Expand
Tetrabutylammonium bromide and K2CO3: an eco-benign catalyst for the synthesis of 5-arylidene-1,3-thiazolidine- 2,4-diones via Knoevenagel condensation
Phase-transfer catalyzed, energy-efficient and facile synthesis of 5-arylidene-1,3-thiazolidine-2,4-diones was developed. Three independent variables (temperature, bases and phase-transfer catalystExpand
Crystal structure of ethyl (E)-4-(4-chlorophenyl)-4-methoxy-2-oxobut-3-enoate
In the title compound, C13H13ClO4, the dihedral angle between the chlorobenezene ring and the least-squares plane through the 4-methoxy-2-oxobut-3-enoate ethyl ester residue is 54.10 (5)°, generating a supramolecular layer in the ac plane. Expand
Antifungal Susceptibility, Exoenzyme Production and Cytotoxicity of Novel Oximes against Candida
Novel oximes synthesized showed lower fungicidal activities than fluconazole but interfered significantly with the expression of phospholipase, which suggests that compounds of this class may interfere with host infection and disease progression. Expand
The title compound [systematic name: (E)-2-hydroxy-5-(phenyldiazenyl)cyclohepta-2,4,6-trien-1-one], C13H10N2O2, is essentially planar with an r.m.s. deviation of 0.036 (2) Å and a dihedral angle ofExpand
Bis(diphenyl-p-tolylphosphane-κP)(2-hydroxy-3,5,7-bromocyclohepta-2,4,6-trienonato-κ2 O,O′)copper(I)
  • N. I. Barnard, T. Hill
  • Chemistry, Medicine
  • Acta crystallographica. Section E, Structure reports online
  • 2012
Within the crystal, extensive weak C—H⋯π interactions contribute to the herringbone pattern observed in the packing of the molecules. Expand