S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.


Inhibitors of apoptosis (IAPs) are a family of highly-conserved proteins that regulate cell survival through binding to caspases, the final executioners of apoptosis. X-linked IAP (XIAP) is the most widely expressed IAP and plays an important function in regulating cell survival. XIAP contains 3 baculoviral IAP repeats (BIRs) followed by a RING finger… (More)
DOI: 10.1073/pnas.0810595106


7 Figures and Tables