S-nitrosothiol-modified dendrimers as nitric oxide delivery vehicles.

@article{Stasko2008SnitrosothiolmodifiedDA,
  title={S-nitrosothiol-modified dendrimers as nitric oxide delivery vehicles.},
  author={Nathan A Stasko and Thomas H. Fischer and Mark H Schoenfisch},
  journal={Biomacromolecules},
  year={2008},
  volume={9 3},
  pages={834-41}
}
The synthesis and characterization of two generation-4 polyamidoamine (PAMAM) dendrimers with S-nitrosothiol exteriors are reported. The hyperbranched macromolecules were modified with either N-acetyl-D, L-penicillamine (NAP) or N-acetyl-L-cysteine (NACys) and analyzed via 1H and 13C NMR, UV absorption spectroscopy, MALDI-TOF mass spectrometry, and size… CONTINUE READING