S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.


Endogenous S-nitrosoglutathione (GSNO) is known to increase the expression of certain proteins at concentrations present in the normal human airway. We hypothesized that GSNO would increase expression and maturation of the cystic fibrosis transmembrane conductance regulator (CFTR). Cells expressing DeltaF508 and wild type CFTR were exposed to GSNO and… (More)


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@article{Zaman2001SnitrosoglutathioneIC, title={S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.}, author={K Zaman and Michael J McPherson and Jane N Vaughan and Jack F.V. Hunt and Filipa Mendes and Benjamin M. Gaston and Lisa A. Palmer}, journal={Biochemical and biophysical research communications}, year={2001}, volume={284 1}, pages={65-70} }