S-adenosylmethionine increases erythrocyte ATP in vitro by a route independent of adenosine kinase.

@article{Montero1990SadenosylmethionineIE,
  title={S-adenosylmethionine increases erythrocyte ATP in vitro by a route independent of adenosine kinase.},
  author={Carmen Montero and Ryszard T Smolenski and J. Duley and H. Anne Simmonds},
  journal={Biochemical pharmacology},
  year={1990},
  volume={40 12},
  pages={2617-23}
}
The mechanism by which S-adenosylmethionine (SAM) and adenosine (Ado) increase ATP levels in intact human erythrocytes in vitro has been compared. The use of erythrocytes from healthy controls and from subjects totally deficient in adenine phosphoribosyltransferase (APRT), plus inhibitors of adenosine kinase (AK) and adenosine deaminase (ADA) separately and together, has enabled us to demonstrate that this increment in ATP levels occurred via totally different metabolic routes. The results show… CONTINUE READING
8 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…