S-adenosylmethionine Administration Attenuates Low Brain-Derived Neurotrophic Factor Expression Induced by Chronic Cerebrovascular Hypoperfusion or Beta Amyloid Treatment

@article{Li2016SadenosylmethionineAA,
  title={S-adenosylmethionine Administration Attenuates Low Brain-Derived Neurotrophic Factor Expression Induced by Chronic Cerebrovascular Hypoperfusion or Beta Amyloid Treatment},
  author={Qian Li and Jing Cui and Chen Fang and Xiaowen Zhang and Liang Li},
  journal={Neuroscience Bulletin},
  year={2016},
  volume={32},
  pages={153-161}
}
Chronic cerebrovascular hypoperfusion is a high-risk factor for Alzheimer’s disease (AD) as it is conducive to beta amyloid (Aβ) over-production. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family widely expressed in the central nervous system. The structure of the rat BDNF gene is complex, consisting of eight non-coding exons (I–VIII) and one coding exon (IX). The BDNF gene is transcribed from multiple promoters located upstream of different 5′ non-coding exons to… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Similar Papers

Loading similar papers…