S-Nitrosothiols: cellular formation and transport.

  title={S-Nitrosothiols: cellular formation and transport.},
  author={Yanhong Zhang and Neil Hogg},
  journal={Free radical biology & medicine},
  volume={38 7},
This review will focus on the transport and intracellular formation of S-nitrosothiols in cell culture models. The major points made in this article are: (1) S-Nitrosothiols are actively metabolized by cells. (2) S-Nitrosothiols affect cells in ways distinctly different from those of nitric oxide and can act through mechanisms that do not involve the intermediacy of nitric oxide. (3) Some S-nitrosothiols (S-nitrosocysteine, S-nitrosohomocysteine) can be taken up into cells via amino acid… CONTINUE READING
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