S-100 protein and neurohistopathologic changes in a porcine model of acute lung injury.

@article{Fries2005S100PA,
  title={S-100 protein and neurohistopathologic changes in a porcine model of acute lung injury.},
  author={M. Fries and Johannes Bickenbach and Dietrich Henzler and Stefan Beckers and Rolf Dembinski and Bernd Sellhaus and Rolf Rossaint and Ralf Kuhlen},
  journal={Anesthesiology},
  year={2005},
  volume={102 4},
  pages={761-7}
}
BACKGROUND Survivors of acute respiratory distress syndrome exhibit neuropsychological sequelae that might be attributable to hippocampal damage. The authors sought to determine the effects of hypoxemia in a pig model of acute lung injury on the hippocampal region and the release of S-100 protein in comparison to a control group in which hypoxemia was induced by reducing the inspired oxygen fraction. METHODS Hypoxemia was induced in 14 female pigs by repeated lung lavages (lung injury group… CONTINUE READING

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