Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3

@article{Booken2008SzarySI,
  title={S{\'e}zary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3},
  author={Nina Booken and Alexei Gratchev and Jochen Utikal and Christoph Wei\ss and Xiao Yu and Muna Qadoumi and Matthias Schmuth and Norbert Sepp and Dorothea Nashan and Knuth Rass and Thomas T{\"u}ting and Chalif Assaf and Edgar Dippel and Rudolf Stadler and C D Klemke and Sergij Goerdt},
  journal={Leukemia},
  year={2008},
  volume={22},
  pages={393-399}
}
Sezary syndrome (SS) is a rare, aggressive CD4+ cutaneous T-cell lymphoma (CTCL); molecular traits differentiating SS from nonleukemic mycosis fungoides (MF) and from inflammatory skin diseases (ID) are not sufficiently characterized. Peripheral blood mononuclear cells (PBMC) of 10 SS patients and 10 healthy donors (HD) were screened by Affymetrix U133Plus2.0 chips for differential gene expression. Ten candidate genes were confirmed by qRT-PCR to be significantly overexpressed in CD4+ T cells… CONTINUE READING