Ryanodine-sensitive component of calcium transients evoked by nerve firing at presynaptic nerve terminals.

@article{Peng1996RyanodinesensitiveCO,
  title={Ryanodine-sensitive component of calcium transients evoked by nerve firing at presynaptic nerve terminals.},
  author={Ying Peng},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1996},
  volume={16 21},
  pages={6703-12}
}
  • Ying Peng
  • Published 1996 in
    The Journal of neuroscience : the official…
Whether Ca2+ released from stores within the presynaptic nerve terminals also contributes to the Ca2+ elevation evoked by action potentials was tested in intact bullfrog sympathetic ganglia. Intraterminal Ca2+ transients (Delta[Ca2+]i) were evoked by electrical shocks to the presynaptic nerves at 20 Hz and were monitored by fura-2 fluorimetry. Ca2+ released through intraterminal ryanodine-sensitive channels accounted for 46% of the peak Ca2+ elevation. Moreover, in half of the terminals when… CONTINUE READING
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