Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies.

Abstract

It has been six years since the first reported link between mutations in the cardiac ryanodine receptor Ca(2+) release channel (RyR2) and catecholaminergic polymorphic ventricular tachycardia (CPVT), a malignant stress-induced arrhythmia. In this time, rapid advances have been made in identifying new mutations, and in understanding how these mutations… (More)

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Cite this paper

@article{George2007RyanodineRA, title={Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies.}, author={Christopher H George and Hala Jundi and Nathan L. Thomas and Debra Lucie Fry and F. Anthony Lai}, journal={Journal of molecular and cellular cardiology}, year={2007}, volume={42 1}, pages={34-50} }