Ryanodine and dihydropyridine receptor binding in ventricular cardiac muscle of fish with different temperature preferences

@article{Tiitu2003RyanodineAD,
  title={Ryanodine and dihydropyridine receptor binding in ventricular cardiac muscle of fish with different temperature preferences},
  author={Virpi Tiitu and Matti Vornanen},
  journal={Journal of Comparative Physiology B},
  year={2003},
  volume={173},
  pages={285-291}
}
Ca2+-induced Ca2+ release (CICR) mechanism of cardiac excitation–contraction (e–c) coupling is dependent on the close apposition between the sarcolemmal dihydropyridine receptors (DHPR) and the sarcoplasmic reticulum (SR) ryanodine receptors (RyR). In particular, high RyR/DHPR ratio is considered to reflect strong dependence on SR Ca2+ stores for the intracellular Ca2+ transient. To indirectly evaluate the significance of CICR in fish hearts, densities of cardiac DHPRs and RyRs were compared in… CONTINUE READING
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Cold acclimation suppresses the contractility of both atrial and ventricular muscle of the crucian carp (Carassius carassius L.) heart

  • V Tiitu, M Vornanen
  • J Fish Biol
  • 2001
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