Ruthenium-NHC-catalyzed asymmetric hydrogenation of flavones and chromones: general access to enantiomerically enriched flavanones, flavanols, chromanones, and chromanols.

Flavanoids and chromanoids including flavanones, flavanols, chromanones, and chromanols are a large family of well-known natural products (Scheme 1). 2] These natural products have been shown to exhibit a wide range of biological activities including anticancer, antitumor, antibacterial, antimicrobial, antioxidant, estrogenic, and antiestrogenic properties… CONTINUE READING