Ruthenium(II) Acetate Catalyst for Direct Functionalisation of sp2-CH Bonds with Aryl Chlorides and Access to Tris- Heterocyclic Molecules

@article{Pogan2009RutheniumIIAC,
  title={Ruthenium(II) Acetate Catalyst for Direct Functionalisation of sp2-CH Bonds with Aryl Chlorides and Access to Tris- Heterocyclic Molecules},
  author={Franc Po{\vz}gan and Pierre H. Dixneuf},
  journal={Advanced Synthesis \& Catalysis},
  year={2009},
  volume={351},
  pages={1737-1743}
}
The in situ generated (p-cymene)ruthenium diacetate [Ru(OAc) 2 (p-cymene)] catalyst 2, prepared from the (p-cymene)ruthenium dichloride dimer {[RuCl 2 ( P -cymene)]2, 1} and potassium acetate (KOAc), acts as an excellent catalyst for ortho C-H bond functionalisation of 2-pyridylbenzene with unactivated aryl chlorides in the presence of potassium carbonate (K,CO 3 ). Quantitative diarylation can be reached in 1 h at 120°C. The diarylation of 2-pyridylbenzene with 2-halopyridines and 2- and 3… 
93 Citations
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