Russian Old Believers: Genetic Consequences of Their Persecution and Exile, as Shown by Mitochondrial DNA Evidence

  title={Russian Old Believers: Genetic Consequences of Their Persecution and Exile, as Shown by Mitochondrial DNA Evidence},
  author={Samara Rubinstein and Matthew C. Dulik and Omer Gokcumen and Sergey I. Zhadanov and L. P. Osipova and Maggie Cocca and Nishi Mehta and Marija Gubina and Olga L. Posukh and Theodore G. Schurr},
  booktitle={Human biology},
Abstract In 1653, the Patriarch Nikon modified liturgical practices to bring the Russian Orthodox Church in line with those of the Eastern (Greek) Orthodox Church, from which it had split 200 years earlier. The Old Believers (staroveri) rejected these changes and continued to worship using the earlier practices. These actions resulted in their persecution by the Russian Orthodox Church, which forced them into exile across Siberia. Given their history, we investigate whether populations of Old… 

Polymorphism of mitochondrial DNA in old believers from Siberia

The polymorphism of mtDNA was examined in populations of Old Believers and Russians from Novosibirsk oblast to confirm the earlier hypothesized influence of the Finno-Ugric component on the East Slavic populations.

Genetic ancestry and indigenous heritage in a Native American descendant community in Bermuda.

Analysis of genetic variation in 111 members of Bermuda's self-proclaimed St. David's Island Native Community reveals that the majority of mitochondrial DNA (mtDNA) and Y-chromosome haplotypes are of African and West Eurasian origin, unlike other English-speaking New World colonies.

Mitochondrial diversity patterns and the Magdalenian resettlement of Europe: new insights from the edge of the Franco-Cantabrian refuge

A new explanation for the population dynamics inside the Franco-Cantabrian area, based on range expansion theory is discussed, compatible with most proposals about the postglacial resettlement of Western Europe.

Genetic heritage and native identity of the Seaconke Wampanoag tribe of Massachusetts.

Comparison of the genetic data with genealogical and historical information allows us to reconstruct the tribal history of the Seaconke Wampanoag back to at least the early 18th century, and indicates that the majority of their mtDNA haplotypes belongs to West Eurasian and African lineages.

Polymorphism of the c-fms, ITGB3, CCR2, and DBH genes in the populations of old believers of the Tyumen oblast and Russian residents of Novosibirsk

The frequencies of the rare alleles of CCR2, ITGB3, and 3'UTR of c-fms in the Old Believers are lower than in the sample of Novosibirsk Russians, and the rare allele of DBH is more frequent, apparently related to the long-term isolation of Old Believer.

Mitochondrial DNA Haplogroups and Susceptibility to Prostate Cancer in a Colombian Population

The mitochondrial DNA hypervariable segment I (HSV-1) was sequenced in a population-based study covering 168 cases and 140 unrelated healthy individuals as a control group (CG).

Peculiarity of Pomors of Onega Peninsula and Winter Coast in the genetic context of Northern Europe

A subtotal study of the gene pool of the Arkhangelsk Oblast Pomors (Onega Coast, Summer Coast, the western fragment of the Winter Coast) using a panel of 60 Y-chromosome SNP markers through multidimensional scaling and mapping of genetic distances.

Genetic Background and Climatic Droplet Keratopathy Incidence in a Mapuche Population from Argentina

The results indicate a lack of correlation between genetic ancestry as represented by haploid genetic systems and the incidence of CDK in Mapuche populations, and the mtDNA appears to play less of a role in CDK expression than for other complex diseases linked to bioenergetic processes.

Genetic Background and CDK in Mapuche Indians Genetic Background and Climatic Droplet Keratopathy Incidence in a Mapuche Population from Argentina : A Case-Control Study

It was found that HLA-DRB*14 had a positive association with incidence of the disease, but the correlation between genetic ancestry as represented by haploid genetic systems and the expression of CDK in Mapuche populations was not observed.



Genetic variation in the enigmatic Altaian Kazakhs of South-Central Russia: insights into Turkic population history.

Analysis of the mtDNAs from 237 Altaian Kazakhs revealed that their mtDNA gene pool was comprised of roughly equal proportions of East (A-G, M7, M13, Y and Z) and West (H, HV, pre-HV, R, IK, JT, X, U) Eurasian haplog groups, with the haplotypic diversity within haplogroups C, D, H, and U being particularly high.

mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World.

The sequence-divergence estimates for haplogroups A, C, and D of Siberian and Native American populations indicate that the earliest inhabitants of Beringia possessed a limited number of founding mtDNA haplotypes and that the first humans expanded into the New World approximately 34,000 years before present.

Mitochondrial DNA variability in Russians and Ukrainians: Implication to the origin of the Eastern Slavs

It is concluded that the Slavonic migrations in early Middle Ages from their putative homeland in central Europe to the east of Europe were accompanied mostly by the same mtDNA types characteristic for the pre‐Slavonic populations of eastern Europe.

Mitochondrial DNA analysis of Mongolian populations and implications for the origin of New World founders.

It is proposed that indigenous populations in east Central Asia represent the closest genetic link between Old and New World populations and is likely that founder effects manifest throughout Asia and the Americas are responsible for differences in mtDNA haplotype frequencies observed in these regions.

Mitochondrial DNA Portrait of Latvians: Towards the Understanding of the Genetic Structure of Baltic‐Speaking Populations

The results of the mtDNA analysis show that the previously described sharp difference between the Y‐chromosomal hg N3 distribution in the paternally inherited gene pool of Baltic‐speaking populations and of other European Indo‐European speakers does not have a corresponding maternal counterpart.

Mitochondrial DNA Variations in Russian and Belorussian Populations

Data of this study support the proposed model of the origin of modern Eastern Slavs, which implies the admixture of ancient Slavonic tribes with pre-Slavonic populations of Eastern Europe, and should contribute to general studies of mitochondrial DNA variations in Europe.

The matrilineal ancestry of Ashkenazi Jewry: portrait of a recent founder event.

It is shown that close to one-half of Ashkenazi Jews can be traced back to only 4 women carrying distinct mtDNAs that are virtually absent in other populations, with the important exception of low frequencies among non-Ashkenazi Jewry.

mtDNA variation of aboriginal Siberians reveals distinct genetic affinities with Native Americans.

The hypothesis that the first humans to move from Siberia to the Americas carried with them a limited number of founding mtDNAs is supported and that the initial migration occurred between 17,000-34,000 years before present.

Mitochondrial DNA variation in two South Siberian Aboriginal populations: implications for the genetic history of North Asia.

The results of nucleotide diversity analysis in East Asian and Siberian populations suggest that Central and East Asia were the source areas from which the genetically heterogeneous Tuvinians and Buryats first emerged.

Mitochondrial DNA Variability in Bosnians and Slovenians

The observed differentiation between Bosnian and Slovenian mtDNAs suggests that at least two different migration waves of the Slavs may have reached the Balkans in the early Middle Ages.